Discovery of diverse thyroid hormone receptor antagonists by high-throughput docking
Treatment of hyperthyroidism, a common clinical condition that can have serious manifestations in the elderly, has remained essentially unchanged for >30 years. Directly antagonizing the effect of the thyroid hormone at the receptor level may be a significant improvement for the treatment of hyperth...
Shranjeno v:
| izdano v: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2003
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC165879/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12777627/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1131854100 |
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