A ligand-reversible dimerization system for controlling protein–protein interactions

Chemically induced dimerization provides a general way to gain control over intracellular processes. Typically, FK506-binding protein (FKBP) domains are fused to a signaling domain of interest, allowing crosslinking to be initiated by addition of a bivalent FKBP ligand. In the course of protein engi...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Rollins, Carl T., Rivera, Victor M., Woolfson, Derek N., Keenan, Terence, Hatada, Marcos, Adams, Susan E., Andrade, Lawrence J., Yaeger, David, van Schravendijk, Marie Rose, Holt, Dennis A., Gilman, Michael, Clackson, Tim
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2000
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16505/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10852943/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.100101997
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