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A Multiprotein Nuclear Complex Connects Fanconi Anemia and Bloom Syndrome
Bloom syndrome (BS) is a genetic disorder associated with dwarfism, immunodeficiency, reduced fertility, and an elevated risk of cancer. To investigate the mechanism of this disease, we isolated from human HeLa extracts three complexes containing the helicase defective in BS, BLM. Interestingly, one...
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| Asıl Yazarlar: | , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Microbiology
2003
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC164758/ https://ncbi.nlm.nih.gov/pubmed/12724401 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.10.3417-3426.2003 |
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