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Evidence for subcomplexes in the Fanconi anemia pathway

Fanconi anemia (FA) is a genomic instability disorder, clinically characterized by congenital abnormalities, progressive bone marrow failure, and predisposition to malignancy. Cells derived from patients with FA display a marked sensitivity to DNA cross-linking agents, such as mitomycin C (MMC). Thi...

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Detalhes bibliográficos
Main Authors: Medhurst, Annette L., Laghmani, El Houari, Steltenpool, Jurgen, Ferrer, Miriam, Fontaine, Chantal, de Groot, Jan, Rooimans, Martin A., Scheper, Rik J., Meetei, Amom Ruhikanta, Wang, Weidong, Joenje, Hans, de Winter, Johan P.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Hematology 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895538/
https://ncbi.nlm.nih.gov/pubmed/16720839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-11-008151
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