FAAP100 is essential for activation of the Fanconi anemia-associated DNA damage response pathway

The Fanconi anemia (FA) core complex plays a central role in the DNA damage response network involving breast cancer susceptibility gene products, BRCA1 and BRCA2. The complex consists of eight FA proteins, including a ubiquitin ligase (FANCL) and a DNA translocase (FANCM), and is essential for mono...

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Bibliographische Detailangaben
Hauptverfasser: Ling, Chen, Ishiai, Masamichi, Ali, Abdullah Mahmood, Medhurst, Annette L, Neveling, Kornelia, Kalb, Reinhard, Yan, Zhijiang, Xue, Yutong, Oostra, Anneke B, Auerbach, Arleen D, Hoatlin, Maureen E, Schindler, Detlev, Joenje, Hans, de Winter, Johan P, Takata, Minoru, Meetei, Amom Ruhikanta, Wang, Weidong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2007
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852792/
https://ncbi.nlm.nih.gov/pubmed/17396147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601666
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