FAAP100 is essential for activation of the Fanconi anemia-associated DNA damage response pathway

The Fanconi anemia (FA) core complex plays a central role in the DNA damage response network involving breast cancer susceptibility gene products, BRCA1 and BRCA2. The complex consists of eight FA proteins, including a ubiquitin ligase (FANCL) and a DNA translocase (FANCM), and is essential for mono...

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Bibliographic Details
Main Authors:	Ling, Chen, Ishiai, Masamichi, Ali, Abdullah Mahmood, Medhurst, Annette L, Neveling, Kornelia, Kalb, Reinhard, Yan, Zhijiang, Xue, Yutong, Oostra, Anneke B, Auerbach, Arleen D, Hoatlin, Maureen E, Schindler, Detlev, Joenje, Hans, de Winter, Johan P, Takata, Minoru, Meetei, Amom Ruhikanta, Wang, Weidong
Format:	Artigo
Language:	Inglês
Published:	Nature Publishing Group 2007
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC1852792/ https://ncbi.nlm.nih.gov/pubmed/17396147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601666
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FAAP100 is essential for activation of the Fanconi anemia-associated DNA damage response pathway

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