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FAAP100 is essential for activation of the Fanconi anemia-associated DNA damage response pathway
The Fanconi anemia (FA) core complex plays a central role in the DNA damage response network involving breast cancer susceptibility gene products, BRCA1 and BRCA2. The complex consists of eight FA proteins, including a ubiquitin ligase (FANCL) and a DNA translocase (FANCM), and is essential for mono...
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| Главные авторы: | , , , , , , , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1852792/ https://ncbi.nlm.nih.gov/pubmed/17396147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601666 |
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