FAAP100 is essential for activation of the Fanconi anemia-associated DNA damage response pathway

The Fanconi anemia (FA) core complex plays a central role in the DNA damage response network involving breast cancer susceptibility gene products, BRCA1 and BRCA2. The complex consists of eight FA proteins, including a ubiquitin ligase (FANCL) and a DNA translocase (FANCM), and is essential for mono...

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Autori principali: Ling, Chen, Ishiai, Masamichi, Ali, Abdullah Mahmood, Medhurst, Annette L, Neveling, Kornelia, Kalb, Reinhard, Yan, Zhijiang, Xue, Yutong, Oostra, Anneke B, Auerbach, Arleen D, Hoatlin, Maureen E, Schindler, Detlev, Joenje, Hans, de Winter, Johan P, Takata, Minoru, Meetei, Amom Ruhikanta, Wang, Weidong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2007
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852792/
https://ncbi.nlm.nih.gov/pubmed/17396147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601666
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