Caricamento...

A Multiprotein Nuclear Complex Connects Fanconi Anemia and Bloom Syndrome

Bloom syndrome (BS) is a genetic disorder associated with dwarfism, immunodeficiency, reduced fertility, and an elevated risk of cancer. To investigate the mechanism of this disease, we isolated from human HeLa extracts three complexes containing the helicase defective in BS, BLM. Interestingly, one...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Meetei, Amom Ruhikanta, Sechi, Salvatore, Wallisch, Michael, Yang, Dafeng, Young, Mary K., Joenje, Hans, Hoatlin, Maureen E., Wang, Weidong
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2003
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC164758/
https://ncbi.nlm.nih.gov/pubmed/12724401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.10.3417-3426.2003
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !