A Multiprotein Nuclear Complex Connects Fanconi Anemia and Bloom Syndrome

Bloom syndrome (BS) is a genetic disorder associated with dwarfism, immunodeficiency, reduced fertility, and an elevated risk of cancer. To investigate the mechanism of this disease, we isolated from human HeLa extracts three complexes containing the helicase defective in BS, BLM. Interestingly, one...

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Detalhes bibliográficos
Main Authors: Meetei, Amom Ruhikanta, Sechi, Salvatore, Wallisch, Michael, Yang, Dafeng, Young, Mary K., Joenje, Hans, Hoatlin, Maureen E., Wang, Weidong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
DNA Dynamics and Chromosome Structure
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC164758/
https://ncbi.nlm.nih.gov/pubmed/12724401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.10.3417-3426.2003
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