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A Multiprotein Nuclear Complex Connects Fanconi Anemia and Bloom Syndrome
Bloom syndrome (BS) is a genetic disorder associated with dwarfism, immunodeficiency, reduced fertility, and an elevated risk of cancer. To investigate the mechanism of this disease, we isolated from human HeLa extracts three complexes containing the helicase defective in BS, BLM. Interestingly, one...
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| Main Authors: | , , , , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
American Society for Microbiology
2003
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC164758/ https://ncbi.nlm.nih.gov/pubmed/12724401 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.10.3417-3426.2003 |
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