A Multiprotein Nuclear Complex Connects Fanconi Anemia and Bloom Syndrome

Bloom syndrome (BS) is a genetic disorder associated with dwarfism, immunodeficiency, reduced fertility, and an elevated risk of cancer. To investigate the mechanism of this disease, we isolated from human HeLa extracts three complexes containing the helicase defective in BS, BLM. Interestingly, one...

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Bibliografiset tiedot
Päätekijät: Meetei, Amom Ruhikanta, Sechi, Salvatore, Wallisch, Michael, Yang, Dafeng, Young, Mary K., Joenje, Hans, Hoatlin, Maureen E., Wang, Weidong
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2003
Aiheet:
DNA Dynamics and Chromosome Structure
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC164758/
https://ncbi.nlm.nih.gov/pubmed/12724401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.10.3417-3426.2003
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