Single-molecule detection of DNA hybridization
We demonstrate the detection of nanometer-scale conformational changes of single DNA oligomers through a micromechanical technique. The quantity monitored is the displacement of a micrometer-size bead tethered to a surface by the probe molecule undergoing the conformational change. This technique al...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2003
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164633/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12808129/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1337215100 |
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