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Single-molecule detection of DNA hybridization
We demonstrate the detection of nanometer-scale conformational changes of single DNA oligomers through a micromechanical technique. The quantity monitored is the displacement of a micrometer-size bead tethered to a surface by the probe molecule undergoing the conformational change. This technique al...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC164633/ https://ncbi.nlm.nih.gov/pubmed/12808129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1337215100 |
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