Single-molecule detection of DNA hybridization
We demonstrate the detection of nanometer-scale conformational changes of single DNA oligomers through a micromechanical technique. The quantity monitored is the displacement of a micrometer-size bead tethered to a surface by the probe molecule undergoing the conformational change. This technique al...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2003
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164633/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12808129/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1337215100 |
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