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Association of 14-3-3 Proteins to β(1)-Adrenergic Receptors Modulates Kv11.1 K(+) Channel Activity in Recombinant Systems

We identify a new mechanism for the β(1)-adrenergic receptor (β(1)AR)-mediated regulation of human ether-a-go-go–related gene (HERG) potassium channel (Kv11.1). We find that the previously reported modulatory interaction between Kv11.1 channels and 14-3-3ε proteins is competed by wild type β(1)AR by...

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Detalhes bibliográficos
Main Authors: Tutor, Antonio S., Delpón, Eva, Caballero, Ricardo, Gómez, Ricardo, Núñez, Lucía, Vaquero, Miguel, Tamargo, Juan, Mayor, Federico, Penela, Petronila
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635398/
https://ncbi.nlm.nih.gov/pubmed/16914520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-05-0422
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