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Homing endonuclease I-CreI derivatives with novel DNA target specificities
Homing endonucleases are highly specific enzymes, capable of recognizing and cleaving unique DNA sequences in complex genomes. Since such DNA cleavage events can result in targeted allele-inactivation and/or allele-replacement in vivo, the ability to engineer homing endonucleases matched to specific...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2006
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1635285/ https://ncbi.nlm.nih.gov/pubmed/16971456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl645 |
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