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Expression of I-CreI Endonuclease Generates Deletions Within the rDNA of Drosophila

The rDNA arrays in Drosophila contain the cis-acting nucleolus organizer regions responsible for forming the nucleolus and the genes for the 28S, 18S, and 5.8S/2S RNA components of the ribosomes and so serve a central role in protein synthesis. Mutations or alterations that affect the nucleolus orga...

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Autores principales: Paredes, Silvana, Maggert, Keith A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Genetics Society of America 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666528/
https://ncbi.nlm.nih.gov/pubmed/19171942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.108.099093
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