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Highly Efficient Sex Chromosome Interchanges Produced By I-CreI Expression in Drosophila

The homing endonuclease I-CreI recognizes a site in the gene encoding the 23S rRNA of Chlamydomonas reinhardtii. A very similar sequence is present in the 28S rRNA genes that are located on the X and Y chromosomes of Drosophila melanogaster. In this work we show that I-CreI expression in Drosophila...

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Detalhes bibliográficos
Main Authors: Maggert, Keith A., Golic, Kent G.
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright © 2005 by the Genetics Society of America 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456814/
https://ncbi.nlm.nih.gov/pubmed/16020774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.040071
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