Homing endonuclease I-CreI derivatives with novel DNA target specificities

Homing endonucleases are highly specific enzymes, capable of recognizing and cleaving unique DNA sequences in complex genomes. Since such DNA cleavage events can result in targeted allele-inactivation and/or allele-replacement in vivo, the ability to engineer homing endonucleases matched to specific...

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Detaylı Bibliyografya
Asıl Yazarlar: Rosen, Laura E., Morrison, Holly A., Masri, Selma, Brown, Michael J., Springstubb, Brendan, Sussman, Django, Stoddard, Barry L., Seligman, Lenny M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2006
Konular:
Nucleic Acid Enzymes
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635285/
https://ncbi.nlm.nih.gov/pubmed/16971456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl645
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