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Antigen Processing of the Heptavalent Pneumococcal Conjugate Vaccine Carrier Protein CRM(197) Differs Depending on the Serotype of the Attached Polysaccharide
The pneumococcal (Pn) conjugate vaccine includes seven different polysaccharides (PS) conjugated to CRM(197). Utilizing antigen-processing cells and a CRM(197)-specific mouse T-cell hybridoma, we found that the serotype of conjugated PnPS dramatically affected antigen processing of CRM(197). Unconju...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology
2003
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC161992/ https://ncbi.nlm.nih.gov/pubmed/12819115 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.7.4186-4189.2003 |
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