Antigen Processing of the Heptavalent Pneumococcal Conjugate Vaccine Carrier Protein CRM(197) Differs Depending on the Serotype of the Attached Polysaccharide

The pneumococcal (Pn) conjugate vaccine includes seven different polysaccharides (PS) conjugated to CRM(197). Utilizing antigen-processing cells and a CRM(197)-specific mouse T-cell hybridoma, we found that the serotype of conjugated PnPS dramatically affected antigen processing of CRM(197). Unconju...

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Bibliografske podrobnosti
Main Authors: Leonard, Ethan G., Canaday, David H., Harding, Clifford V., Schreiber, John R.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2003
Teme:
Microbial Immunity and Vaccines
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC161992/
https://ncbi.nlm.nih.gov/pubmed/12819115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.7.4186-4189.2003
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