Pneumococcal Conjugate Vaccines Overcome Splenic Dependency of Antibody Response to Pneumococcal Polysaccharides

Protection against infections with Streptococcus pneumoniae depends on the presence of antibodies against capsular polysaccharides that facilitate phagocytosis. Asplenic patients are at increased risk for pneumococcal infections, since both phagocytosis and the initiation of the antibody response to...

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Autori principali: Breukels, Mijke A., Zandvoort, Andre, van den Dobbelsteen, Germie P. J. M., van den Muijsenberg, Adrie, Lodewijk, Monique E., Beurret, Michel, Klok, Pieter A., Timens, Wim, Rijkers, Ger T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2001
Soggetti:
Microbial Immunity and Vaccines
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC98850/
https://ncbi.nlm.nih.gov/pubmed/11705936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.12.7583-7587.2001
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