Pneumococcal Conjugate Vaccines Overcome Splenic Dependency of Antibody Response to Pneumococcal Polysaccharides

Protection against infections with Streptococcus pneumoniae depends on the presence of antibodies against capsular polysaccharides that facilitate phagocytosis. Asplenic patients are at increased risk for pneumococcal infections, since both phagocytosis and the initiation of the antibody response to...

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Detalhes bibliográficos
Main Authors: Breukels, Mijke A., Zandvoort, Andre, van den Dobbelsteen, Germie P. J. M., van den Muijsenberg, Adrie, Lodewijk, Monique E., Beurret, Michel, Klok, Pieter A., Timens, Wim, Rijkers, Ger T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC98850/
https://ncbi.nlm.nih.gov/pubmed/11705936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.12.7583-7587.2001
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