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Pneumococcal Conjugate Vaccines Overcome Splenic Dependency of Antibody Response to Pneumococcal Polysaccharides

Protection against infections with Streptococcus pneumoniae depends on the presence of antibodies against capsular polysaccharides that facilitate phagocytosis. Asplenic patients are at increased risk for pneumococcal infections, since both phagocytosis and the initiation of the antibody response to...

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Published in:Infect Immun
Main Authors: Breukels, Mijke A., Zandvoort, Andre, van den Dobbelsteen, Germie P. J. M., van den Muijsenberg, Adrie, Lodewijk, Monique E., Beurret, Michel, Klok, Pieter A., Timens, Wim, Rijkers, Ger T.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2001
Subjects:
Microbial Immunity and Vaccines
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98850/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11705936/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.12.7583-7587.2001
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