Alternate Polypurine Tracts Affect Rous Sarcoma Virus Integration In Vivo

When the endogenous polypurine tract (PPT) of the Rous sarcoma virus (RSV)-derived vector RSVP(A)Z was replaced with alternate retroviral PPTs, the fraction of unintegrated viral DNA with the normal consensus ends significantly decreased and the retention of part of the PPT significantly increased....

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Bibliografiske detaljer
Main Authors: Oh, Jangsuk, Chang, Kevin W., Alvord, W. Gregory, Hughes, Stephen H.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2006
Fag:
Genome Replication and Regulation of Viral Gene Expression
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1617299/
https://ncbi.nlm.nih.gov/pubmed/17005708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00361-06
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