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Mutations in the U5 Sequences Adjacent to the Primer Binding Site Do Not Affect tRNA Cleavage by Rous Sarcoma Virus RNase H but Do Cause Aberrant Integrations In Vivo

In most retroviruses, the first nucleotide added to the tRNA primer becomes the right end of the U5 region in the right long terminal repeat (LTR); the removal of this tRNA primer by RNase H defines the right end of the linear double-stranded DNA. Most retroviruses have two nucleotides between the 5...

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Bibliografiset tiedot
Päätekijät: Oh, Jangsuk, Chang, Kevin W., Hughes, Stephen H.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2006
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1317513/
https://ncbi.nlm.nih.gov/pubmed/16352569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.1.451-459.2006
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