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Alternate Polypurine Tracts Affect Rous Sarcoma Virus Integration In Vivo

When the endogenous polypurine tract (PPT) of the Rous sarcoma virus (RSV)-derived vector RSVP(A)Z was replaced with alternate retroviral PPTs, the fraction of unintegrated viral DNA with the normal consensus ends significantly decreased and the retention of part of the PPT significantly increased....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Oh, Jangsuk, Chang, Kevin W., Alvord, W. Gregory, Hughes, Stephen H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1617299/
https://ncbi.nlm.nih.gov/pubmed/17005708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00361-06
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