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Alternate Polypurine Tracts Affect Rous Sarcoma Virus Integration In Vivo

When the endogenous polypurine tract (PPT) of the Rous sarcoma virus (RSV)-derived vector RSVP(A)Z was replaced with alternate retroviral PPTs, the fraction of unintegrated viral DNA with the normal consensus ends significantly decreased and the retention of part of the PPT significantly increased....

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Detalles Bibliográficos
Main Authors: Oh, Jangsuk, Chang, Kevin W., Alvord, W. Gregory, Hughes, Stephen H.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1617299/
https://ncbi.nlm.nih.gov/pubmed/17005708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00361-06
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