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Increased Production of Folate by Metabolic Engineering of Lactococcus lactis

The dairy starter bacterium Lactococcus lactis is able to synthesize folate and accumulates large amounts of folate, predominantly in the polyglutamyl form. Only small amounts of the produced folate are released in the extracellular medium. Five genes involved in folate biosynthesis were identified...

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Vydáno v:Appl Environ Microbiol
Hlavní autoři: Sybesma, Wilbert, Starrenburg, Marjo, Kleerebezem, Michiel, Mierau, Igor, de Vos, Willem M., Hugenholtz, Jeroen
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC161528/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12788700/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AEM.69.6.3069-3076.2003
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