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Increased Production of Folate by Metabolic Engineering of Lactococcus lactis

The dairy starter bacterium Lactococcus lactis is able to synthesize folate and accumulates large amounts of folate, predominantly in the polyglutamyl form. Only small amounts of the produced folate are released in the extracellular medium. Five genes involved in folate biosynthesis were identified...

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Detalhes bibliográficos
Main Authors: Sybesma, Wilbert, Starrenburg, Marjo, Kleerebezem, Michiel, Mierau, Igor, de Vos, Willem M., Hugenholtz, Jeroen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC161528/
https://ncbi.nlm.nih.gov/pubmed/12788700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.69.6.3069-3076.2003
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