Increased Production of Folate by Metabolic Engineering of Lactococcus lactis

The dairy starter bacterium Lactococcus lactis is able to synthesize folate and accumulates large amounts of folate, predominantly in the polyglutamyl form. Only small amounts of the produced folate are released in the extracellular medium. Five genes involved in folate biosynthesis were identified...

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Bibliografiske detaljer
Main Authors: Sybesma, Wilbert, Starrenburg, Marjo, Kleerebezem, Michiel, Mierau, Igor, de Vos, Willem M., Hugenholtz, Jeroen
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2003
Fag:
Food Microbiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC161528/
https://ncbi.nlm.nih.gov/pubmed/12788700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.69.6.3069-3076.2003
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