Increased Production of Folate by Metabolic Engineering of Lactococcus lactis

The dairy starter bacterium Lactococcus lactis is able to synthesize folate and accumulates large amounts of folate, predominantly in the polyglutamyl form. Only small amounts of the produced folate are released in the extracellular medium. Five genes involved in folate biosynthesis were identified...

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Pubblicato in:	Appl Environ Microbiol
Autori principali:	Sybesma, Wilbert, Starrenburg, Marjo, Kleerebezem, Michiel, Mierau, Igor, de Vos, Willem M., Hugenholtz, Jeroen
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2003
Soggetti:	Food Microbiology
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC161528/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12788700/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AEM.69.6.3069-3076.2003
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