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Efficacy of Ambruticin Analogs in a Murine Model of Invasive Pulmonary Aspergillosis
Ambruticins are a family of polyketides. The antifungal activity of an ambruticin, KOSN-2079, was tested in the mouse model of invasive aspergillosis. KOSN-2079 significantly reduced pulmonary fungal burdens and improved survival over that with the vehicle control. These results support the continue...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1610070/ https://ncbi.nlm.nih.gov/pubmed/17005833 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00558-06 |
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