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Efficacy of Ambruticin Analogs in a Murine Model of Invasive Pulmonary Aspergillosis

Ambruticins are a family of polyketides. The antifungal activity of an ambruticin, KOSN-2079, was tested in the mouse model of invasive aspergillosis. KOSN-2079 significantly reduced pulmonary fungal burdens and improved survival over that with the vehicle control. These results support the continue...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Chiang, Lisa Y., Ejzykowicz, Daniele E., Tian, Zong-Qiang, Katz, Leonard, Filler, Scott G.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2006
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC1610070/
https://ncbi.nlm.nih.gov/pubmed/17005833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00558-06
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