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Novel Inhalational Murine Model of Invasive Pulmonary Aspergillosis
We developed a novel model of invasive aspergillosis (IA) that recapitulates human disease. Mice were immunosuppressed with cyclophosphamide and cortisone acetate and then infected in an aerosol chamber. This procedure reproducibly delivered 1 × 10(3) to 3 × 10(3) conidia to the lungs. Lethal pulmon...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology
2004
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC400587/ https://ncbi.nlm.nih.gov/pubmed/15105158 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.5.1908-1911.2004 |
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