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Efficacy of Ambruticin Analogs in a Murine Model of Coccidioidomycosis

Ambruticin S, an antifungal cyclopropyl-pyran acid, showed curative effects against murine coccidioidal infection. Two analogs of this compound with greater in vitro potency were tested against lethal murine Coccidioides infection. Both improved the survival of mice over that of controls; one result...

詳細記述

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書誌詳細
主要な著者: Shubitz, Lisa F., Galgiani, John N., Tian, Zong-Qiang, Zhong, Ziyang, Timmermans, Pieter, Katz, Leonard
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1610061/
https://ncbi.nlm.nih.gov/pubmed/17005834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00670-06
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