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Efficacy of Ambruticin Analogs in a Murine Model of Coccidioidomycosis

Ambruticin S, an antifungal cyclopropyl-pyran acid, showed curative effects against murine coccidioidal infection. Two analogs of this compound with greater in vitro potency were tested against lethal murine Coccidioides infection. Both improved the survival of mice over that of controls; one result...

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Detalhes bibliográficos
Main Authors: Shubitz, Lisa F., Galgiani, John N., Tian, Zong-Qiang, Zhong, Ziyang, Timmermans, Pieter, Katz, Leonard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1610061/
https://ncbi.nlm.nih.gov/pubmed/17005834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00670-06
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