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Efficacy of Ambruticin Analogs in a Murine Model of Coccidioidomycosis

Ambruticin S, an antifungal cyclopropyl-pyran acid, showed curative effects against murine coccidioidal infection. Two analogs of this compound with greater in vitro potency were tested against lethal murine Coccidioides infection. Both improved the survival of mice over that of controls; one result...

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Detaylı Bibliyografya
Asıl Yazarlar: Shubitz, Lisa F., Galgiani, John N., Tian, Zong-Qiang, Zhong, Ziyang, Timmermans, Pieter, Katz, Leonard
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2006
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1610061/
https://ncbi.nlm.nih.gov/pubmed/17005834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00670-06
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