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Efficacy of Ambruticin Analogs in a Murine Model of Coccidioidomycosis

Ambruticin S, an antifungal cyclopropyl-pyran acid, showed curative effects against murine coccidioidal infection. Two analogs of this compound with greater in vitro potency were tested against lethal murine Coccidioides infection. Both improved the survival of mice over that of controls; one result...

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Hlavní autoři: Shubitz, Lisa F., Galgiani, John N., Tian, Zong-Qiang, Zhong, Ziyang, Timmermans, Pieter, Katz, Leonard
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1610061/
https://ncbi.nlm.nih.gov/pubmed/17005834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00670-06
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