SCF(β-TrCP1) Controls Smad4 Protein Stability in Pancreatic Cancer Cells

Smad4, also known as deleted in pancreatic carcinoma locus 4 (DPC4), is a critical co-factor in signal transduction pathways activated by transforming growth factor (TGF)-β-related ligands that regulate cell growth and differentiation. Mutations in Smad4/DPC4 have been identified in ∼50% of pancreat...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Wan, Mei, Huang, Jin, Jhala, Nirag C., Tytler, Ewan M., Yang, Lei, Vickers, Selwyn M., Tang, Yi, Lu, Chongyuan, Wang, Ning, Cao, Xu
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2005
Soggetti:
Original Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1606393/
https://ncbi.nlm.nih.gov/pubmed/15855639
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi