Negative Regulation of Prolactin Receptor Stability and Signaling Mediated by SCF(β-TrCP) E3 Ubiquitin Ligase

Ubiquitin-dependent degradation of hormone receptors is emerging as a key mechanism that regulates the magnitude and duration of hormonal effects on cells and tissues. The pituitary hormone prolactin (PRL) is involved in regulating cell differentiation, proliferation, and survival. PRL engages its r...

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Bibliografiske detaljer
Main Authors: Li, Ying, Suresh Kumar, K. G., Tang, Weigang, Spiegelman, Vladimir S., Fuchs, Serge Y.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2004
Fag:
Cell Growth and Development
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC387770/
https://ncbi.nlm.nih.gov/pubmed/15082796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.9.4038-4048.2004
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