Negative Regulation of Prolactin Receptor Stability and Signaling Mediated by SCF(β-TrCP) E3 Ubiquitin Ligase

Ubiquitin-dependent degradation of hormone receptors is emerging as a key mechanism that regulates the magnitude and duration of hormonal effects on cells and tissues. The pituitary hormone prolactin (PRL) is involved in regulating cell differentiation, proliferation, and survival. PRL engages its r...

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Detalhes bibliográficos
Main Authors: Li, Ying, Suresh Kumar, K. G., Tang, Weigang, Spiegelman, Vladimir S., Fuchs, Serge Y.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC387770/
https://ncbi.nlm.nih.gov/pubmed/15082796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.9.4038-4048.2004
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