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Negative Regulation of Prolactin Receptor Stability and Signaling Mediated by SCF(β-TrCP) E3 Ubiquitin Ligase

Ubiquitin-dependent degradation of hormone receptors is emerging as a key mechanism that regulates the magnitude and duration of hormonal effects on cells and tissues. The pituitary hormone prolactin (PRL) is involved in regulating cell differentiation, proliferation, and survival. PRL engages its r...

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Bibliografische Detailangaben
Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Li, Ying, Suresh Kumar, K. G., Tang, Weigang, Spiegelman, Vladimir S., Fuchs, Serge Y.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2004
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC387770/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15082796/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.9.4038-4048.2004
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