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Negative Regulation of Prolactin Receptor Stability and Signaling Mediated by SCF(β-TrCP) E3 Ubiquitin Ligase
Ubiquitin-dependent degradation of hormone receptors is emerging as a key mechanism that regulates the magnitude and duration of hormonal effects on cells and tissues. The pituitary hormone prolactin (PRL) is involved in regulating cell differentiation, proliferation, and survival. PRL engages its r...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology
2004
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC387770/ https://ncbi.nlm.nih.gov/pubmed/15082796 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.9.4038-4048.2004 |
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