Hyperphosphorylated tau and neurofilament and cytoskeletal disruptions in mice overexpressing human p25, an activator of cdk5

Hyperphosphorylation of microtubule-associated proteins such as tau and neurofilament may underlie the cytoskeletal abnormalities and neuronal death seen in several neurodegenerative diseases including Alzheimer's disease. One potential mechanism of microtubule-associated protein hyperphosphory...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ahlijanian, Michael K., Barrezueta, Nestor X., Williams, Robert D., Jakowski, Amy, Kowsz, Kim P., McCarthy, Sheryl, Coskran, Timothy, Carlo, Anthony, Seymour, Patricia A., Burkhardt, John E., Nelson, Robert B., McNeish, John D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The National Academy of Sciences 2000
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC16029/
https://ncbi.nlm.nih.gov/pubmed/10706614
Tagiau: Ychwanegu Tag
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