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Deregulation of cdk5, Hyperphosphorylation, and Cytoskeletal Pathology in the Niemann–Pick Type C Murine Model

NPC-1 gene mutations cause Niemann–Pick type C (NPC), a neurodegenerative storage disease resulting in premature death in humans. Spontaneous mutation of the NPC-1 gene in mice generates a similar phenotype, usually with death ensuing by 12 weeks of age. Both human and murine NPC are characterized n...

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Detaylı Bibliyografya
Yayımlandı:J Neurosci
Asıl Yazarlar: Bu, Bitao, Li, Jin, Davies, Peter, Vincent, Inez
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Society for Neuroscience 2002
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6758154/
https://ncbi.nlm.nih.gov/pubmed/12151531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-15-06515.2002
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