Cyclosporin A enhances colchicine-induced apoptosis in rat cerebellar granule neurons

1. Cyclosporin A (CsA, 1–50 μM), an immunosuppressive drug with known neurotoxic effects, did not decrease the viability of primary cultures of rat cerebellar granule neurons (CGN) or induce apoptotic features. However, CsA specifically enhanced the cytotoxicity and apoptosis induced by colchicine (...

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Bibliografiset tiedot
Päätekijät: Canudas, Anna Maria, Jordà, Elvira G, Verdaguer, Ester, Jiménez, Andrés, Sureda, Francesc Xavier, Rimbau, Víctor, Camins, Antoni, Pallàs, Mercè
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2004
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Papers
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1574246/
https://ncbi.nlm.nih.gov/pubmed/14976124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705664
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