Cyclosporin A enhances colchicine-induced apoptosis in rat cerebellar granule neurons

1. Cyclosporin A (CsA, 1–50 μM), an immunosuppressive drug with known neurotoxic effects, did not decrease the viability of primary cultures of rat cerebellar granule neurons (CGN) or induce apoptotic features. However, CsA specifically enhanced the cytotoxicity and apoptosis induced by colchicine (...

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Main Authors: Canudas, Anna Maria, Jordà, Elvira G, Verdaguer, Ester, Jiménez, Andrés, Sureda, Francesc Xavier, Rimbau, Víctor, Camins, Antoni, Pallàs, Mercè
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2004
Ábhair:
Papers
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1574246/
https://ncbi.nlm.nih.gov/pubmed/14976124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705664
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