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Cyclosporin A enhances colchicine-induced apoptosis in rat cerebellar granule neurons
1. Cyclosporin A (CsA, 1–50 μM), an immunosuppressive drug with known neurotoxic effects, did not decrease the viability of primary cultures of rat cerebellar granule neurons (CGN) or induce apoptotic features. However, CsA specifically enhanced the cytotoxicity and apoptosis induced by colchicine (...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2004
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1574246/ https://ncbi.nlm.nih.gov/pubmed/14976124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705664 |
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