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Orphenadrine prevents 3-nitropropionic acid-induced neurotoxicity in vitro and in vivo

1. Previous studies indicate that 3-nitropropionic acid (3-NPA) neurotoxicity involves the excitotoxic activation of N-methyl-D-aspartate (NMDA) receptors. Thus, we examined the effect of orphenadrine (an anticholinergic drug with NMDA receptor antagonist properties) on 3-NPA neurotoxicity in both c...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Pubill, David, Verdaguer, Ester, Canudas, Anna Ma, Sureda, Francesc Xavier, Escubedo, Elena, Camarasa, Jordi, Pallàs, Merce, Camins, Antoni
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2001
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572610/
https://ncbi.nlm.nih.gov/pubmed/11159722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703869
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