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Orphenadrine prevents 3-nitropropionic acid-induced neurotoxicity in vitro and in vivo
1. Previous studies indicate that 3-nitropropionic acid (3-NPA) neurotoxicity involves the excitotoxic activation of N-methyl-D-aspartate (NMDA) receptors. Thus, we examined the effect of orphenadrine (an anticholinergic drug with NMDA receptor antagonist properties) on 3-NPA neurotoxicity in both c...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1572610/ https://ncbi.nlm.nih.gov/pubmed/11159722 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703869 |
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