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Inhibition of the cdk5/MEF2 pathway is involved in the antiapoptotic properties of calpain inhibitors in cerebellar neurons

1. Experimental data implicate calpain activation in the pathways involved in neuronal apoptosis. Indeed, calpain inhibitors confer neuroprotection in response to various neurotoxic stimuli. However, the pathways involved in calpain activation-induced apoptosis are not well known. 2. We demonstrate...

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Autors principals: Verdaguer, Ester, Alvira, Daniel, Jiménez, Andrés, Rimbau, Victor, Camins, Antoni, Pallàs, Mercè
Format: Artigo
Idioma:Inglês
Publicat: 2005
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1576230/
https://ncbi.nlm.nih.gov/pubmed/15912127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706280
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