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Inhibition of the cdk5/MEF2 pathway is involved in the antiapoptotic properties of calpain inhibitors in cerebellar neurons

1. Experimental data implicate calpain activation in the pathways involved in neuronal apoptosis. Indeed, calpain inhibitors confer neuroprotection in response to various neurotoxic stimuli. However, the pathways involved in calpain activation-induced apoptosis are not well known. 2. We demonstrate...

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Bibliografiske detaljer
Main Authors: Verdaguer, Ester, Alvira, Daniel, Jiménez, Andrés, Rimbau, Victor, Camins, Antoni, Pallàs, Mercè
Format: Artigo
Sprog:Inglês
Udgivet: 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1576230/
https://ncbi.nlm.nih.gov/pubmed/15912127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706280
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