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Inhibition of the cdk5/MEF2 pathway is involved in the antiapoptotic properties of calpain inhibitors in cerebellar neurons

1. Experimental data implicate calpain activation in the pathways involved in neuronal apoptosis. Indeed, calpain inhibitors confer neuroprotection in response to various neurotoxic stimuli. However, the pathways involved in calpain activation-induced apoptosis are not well known. 2. We demonstrate...

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Detalhes bibliográficos
Main Authors: Verdaguer, Ester, Alvira, Daniel, Jiménez, Andrés, Rimbau, Victor, Camins, Antoni, Pallàs, Mercè
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1576230/
https://ncbi.nlm.nih.gov/pubmed/15912127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706280
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