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The antimalarial agent mefloquine inhibits ATP-sensitive K-channels
1. The aim of this study was to determine whether antimalarial agents inhibit ATP-sensitive potassium (K(ATP)) channels and thereby contribute to the observed side-effects of these drugs. 2. Mefloquine (10–100 μM), but not artenusate (100 μM), stimulated insulin release from pancreatic islets in vit...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2000
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1572394/ https://ncbi.nlm.nih.gov/pubmed/11030725 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703638 |
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