The antimalarial agent mefloquine inhibits ATP-sensitive K-channels

1. The aim of this study was to determine whether antimalarial agents inhibit ATP-sensitive potassium (K(ATP)) channels and thereby contribute to the observed side-effects of these drugs. 2. Mefloquine (10–100 μM), but not artenusate (100 μM), stimulated insulin release from pancreatic islets in vit...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Gribble, Fiona M, Davis, Timothy M E, Higham, Claire E, Clark, Anne, Ashcroft, Frances M
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2000
Gaiak:
Papers
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572394/
https://ncbi.nlm.nih.gov/pubmed/11030725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703638
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