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Functional characterisation of the human cloned 5-HT(7) receptor (long form); antagonist profile of SB-258719

1. The functional profile of the long form of the human cloned 5-HT(7) receptor (designated h5-HT(7(a))) was investigated using a number of 5-HT receptor agonists and antagonists and compared with its binding profile. Receptor function was measured using adenylyl cyclase activity in washed membranes...

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Detalhes bibliográficos
Main Authors: Thomas, David R, Gittins, Susan A, Collin, Lissa L, Middlemiss, Derek N, Riley, Graham, Hagan, Jim, Gloger, Israel, Ellis, Catherine E, Forbes, Ian T, Brown, Anthony M
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565501/
https://ncbi.nlm.nih.gov/pubmed/9720804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701946
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