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The effect of SB-269970, a 5-HT(7) receptor antagonist, on 5-HT release from serotonergic terminals and cell bodies

1. The presence of 5-HT(7) receptor mRNA and protein in 5-HT neurons suggests that this receptor may act as a 5-HT autoreceptor. In this study, the effect of the 5-HT(7) receptor antagonist, SB-269970 ((R)-1-[3-hydroxy phenyl)sulfonyl]-2-[2-(4-methyl-1-piperidinyl)ethyl]pyrrolidine), was investigate...

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Detalhes bibliográficos
Main Authors: Roberts, Claire, Allen, Lucy, Langmead, Christopher J, Hagan, Jim J, Middlemiss, Derek N, Price, Gary W
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572709/
https://ncbi.nlm.nih.gov/pubmed/11264252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703979
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