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An H-bond between two residues from different loops of the acetylcholine binding site contributes to the activation mechanism of nicotinic receptors
The molecular mechanisms of nicotinic receptor activation are still largely unknown. The crystallographic structure of the acetylcholine binding protein (AChBP) reveals a single H-bond between two different acetylcholine binding loops. Within these homologous loops we systematically introduced α4 re...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC156069/ https://ncbi.nlm.nih.gov/pubmed/12727867 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg197 |
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