Critical Elements Determining Diversity in Agonist Binding and Desensitization of Neuronal Nicotinic Acetylcholine Receptors

To identify the molecular determinants underlying the pharmacological diversity of neuronal nicotinic acetylcholine receptors, we compared the α7 homo-oligomeric and α4β2 hetero-oligomeric receptors. Sets of residues from the regions initially identified within the agonist binding site of the α4 sub...

Full description

Saved in:
Bibliographic Details
Published in:J Neurosci
Main Authors: Corringer, Pierre-Jean, Bertrand, Sonia, Bohler, Sébastien, Edelstein, Stuart J., Changeux, Jean-Pierre, Bertrand, Daniel
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 1998
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6792538/
https://ncbi.nlm.nih.gov/pubmed/9425007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.18-02-00648.1998
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items