Critical Elements Determining Diversity in Agonist Binding and Desensitization of Neuronal Nicotinic Acetylcholine Receptors

To identify the molecular determinants underlying the pharmacological diversity of neuronal nicotinic acetylcholine receptors, we compared the α7 homo-oligomeric and α4β2 hetero-oligomeric receptors. Sets of residues from the regions initially identified within the agonist binding site of the α4 sub...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Corringer, Pierre-Jean, Bertrand, Sonia, Bohler, Sébastien, Edelstein, Stuart J., Changeux, Jean-Pierre, Bertrand, Daniel
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 1998
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6792538/
https://ncbi.nlm.nih.gov/pubmed/9425007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.18-02-00648.1998
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