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Models of the extracellular domain of the nicotinic receptors and of agonist- and Ca(2+)-binding sites

We constructed a three-dimensional model of the amino-terminal extracellular domain of three major types of nicotinic acetylcholine receptor, (α7)(5), (α4)(2)(β2)(3), and (α1)(2)β1γδ, on the basis of the recent x-ray structure determination of the molluscan acetylcholine-binding protein. Comparative...

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Autores principales: Le Novère, Nicolas, Grutter, Thomas, Changeux, Jean-Pierre
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences 2002
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC122498/
https://ncbi.nlm.nih.gov/pubmed/11867716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.042699699
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